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Papers of the Week
Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates.
Authors
Lindquist KA, Mecklenburg J, Hovhannisyan AH, Ruparel S, Akopian ANAbstract
Pain sensation has predominantly mechanical modalities in many pain conditions. Mechanically activated (MA) ion channels on sensory neurons underly responsiveness to mechanical stimuli. The study aimed to address gaps in knowledge regarding MA current properties in higher order species such as non-human primates (NHP; common marmosets), and characterization of MA currents in trigeminal (TG) neuronal subtypes.