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Papers of the Week

Papers: 25 May 2024 - 31 May 2024

2024 May 27

Pediatr Blood Cancer


Investigating home-based opioid use among youth with sickle cell disease using ecological momentary assessment.


Valrie C, Crawford BS, Shipman-Lacewell J, Ajibade O, Fuh B, Smith W, Sisler I


Opioids are a common and essential treatment for acute sickle cell disease (SCD) pain. However, opioids carry well-known adverse side effects, including potential development of hyperalgesia and nociplastic pain. We characterized opioid use in youth with SCD using ecological momentary assessment (EMA) data, and investigated the relationships between home-based opioid use, pain, and a range of biopsychosocial factors.