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Papers of the Week

Papers: 2 Sep 2023 - 8 Sep 2023


Medical Devices, Neurobiology, Pharmacology/Drug Development

2023 Sep 07

Int J Clin Pharmacol Ther


Intrathecal drug-infusion system for treating pain in advanced cancer: New research in patient management.


Chen MG, Xiu M, Yang L, Jin HY, Deng LH, Li Y, Chen P


Currently, the treatment of cancer pain in China mainly follows the three-step pain relief principles formulated by the World Health Organization. As research on subarachnoid drug diffusion has intensified, intrathecal drug delivery has been gradually applied in the treatment of diseases, and improved analgesia can be achieved via the continuous infusion of small doses of morphine-derived drugs. This method can not only effectively relieve pain and enhance quality of life but also significantly reduce the incidence of nausea, vomiting, constipation, and other adverse reactions caused by the long-term intensive use of drugs in patients with cancer pain. This study summarizes the development of the intrathecal drug-infusion system for treating cancer pain in patients with advanced cancer and describes the drugs used, the advantages in pain treatment, and key nursing factors before and after device placement to provide a basis for alleviating pain in patients with cancer.