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Papers of the Week
Intraoperative recordings from the posterior superior insula in awake humans with peripheral neuropathic pain.
Authors
Thibes RB, da Cunha PHM, Lapa JDDS, Dongyang L, Pinheiro DS, Iglesio RF, Duarte KP, Silva VA, Kubota GT, Teixeira MJ, Garcia-Larrea L, Bastiji H, Sato JR, de Andrade DCAbstract
The activity profile of the posterior insula in neuropathic pain (NeP) remains largely unexplored. To address this and examine its modulation by somatosensory stimulation, we recorded local field potentials (LFP) in awake patients with NeP undergoing deep brain stimulation (DBS) electrode implantation to the posterior-superior insula (PSI) for analgesic purposes.