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Papers of the Week


Papers: 22 Feb 2025 - 28 Feb 2025


2025 Feb 22


Rheumatology (Oxford)


39985440

Interrelationships of disease activity, central sensitization, psychosocial and lifestyle factors in axial spondyloarthritis.

Authors

Kieskamp SC, van der Kraan Y, Arends S, Wink F, Bos R, Stewart R, Paap D, Spoorenberg A

Abstract

In a substantial portion of patients with axial spondyloarthritis (axSpA), disease activity scores remain high despite anti-inflammatory treatment. This is possibly due to factors beyond active inflammation including different pain mechanisms and psychosocial factors. Therefore, our aim was to build a biopsychosocial model to explore the interrelationships of Axial Spondyloarthritis Disease Activity Score (ASDAS) with central sensitization (CS), psychological and lifestyle factors in patients with axSpA.