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Papers of the Week
Interleukin Receptor Therapeutics Attenuate Inflammation in Canine Synovium following Cruciate Ligament Injury.
Authors
Lemmon EA, Burt KG, Kim SY, Kwok B, Laforest L, Xiao R, Han L, Scanzello CR, Mauck RL, Agnello KAAbstract
In the knee, synovial fibrosis after ligamentous injury is linked to progressive joint pain and stiffness. The objective of this study was to evaluate changes in synovial architecture, mechanical properties, and transcriptional profiles following naturally occurring cruciate ligament injury in canines and to test potential therapeutics that target drivers of synovial inflammation and fibrosis.