Integrative single-cell RNA and ATAC sequencing reveals that the FOXO1-PRDX2-TNF axis regulates tendinopathy.
Authors
Guo J, Tang H, Huang P, Ye X, Tang C, Shu Z, Guo J, Kang X, Shi Y, Zhou B, Liang T, Tang K
Abstract
Tendinopathy, the most common form of chronic tendon disorder, leads to persistent tendon pain and loss of function. Profiling the heterogeneous cellular composition in the tendon microenvironment helps to elucidate rational molecular mechanisms of tendinopathy.
