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Papers of the Week
Insights from triggers and prodromal symptoms on how migraine attacks start: The threshold hypothesis.
Authors
Sebastianelli G, Atalar AÇ, Cetta I, Farham F, Fitzek M, Karatas-Kursun H, Kholodova M, Kukumägi KH, Montisano DA, Onan D, Pantovic A, Skarlet J, Sotnikov D, Caronna E, Pozo-Rosich PAbstract
The prodrome or premonitory phase is the initial phase of a migraine attack, and it is considered as a symptomatic phase in which prodromal symptoms may occur. There is evidence that attacks start 24-48 hours before the headache phase. Individuals with migraine also report several potential triggers for their attacks, which may be mistaken for premonitory symptoms and hinder migraine research.