Browse by Audience
Skip to content
Papers of the Week
Inhibition of spinal Rac1 attenuates chronic inflammatory pain by regulating the activation of astrocytes.
Authors
Wan Y, Zhou J, Zhang P, Lin X, Li HAbstract
Spinal astrocyte-mediated neuroinflammation is an important mechanism for the maintenance of chronic inflammatory pain. Previous studies have investigated that Ras-related C3 botulinum toxin substrate 1 (Rac1) is closely related to astrocyte activation after central nervous system injury. However, the role of Rac1 in astrocyte activation in chronic inflammatory pain has not been reported.