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Papers of the Week
Inhibition of mPFC norepinephrine improved chronic post-thoracotomy pain in adult rats.
Authors
Zhang F, Qiu W, Qing W, Li J, Chang H, Yu R, Zhou Y, Liao QAbstract
Chronic post-thoracotomy pain (CPTP) is characterized by high incidence, long duration, and severity of pain. Medial prefrontal cortex (mPFC) is a brain region closely associated with chronic pain, and norepinephrine is involved in pain regulation. But the role of mPFC norepinephrine in CPTP and its possible mechanism is unclear.