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Papers of the Week
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.
Authors
Su Y, Tian W, Cheng L, Yin L, He X, Wei XAbstract
Endometriosis (EMs), manifested by pain and infertility, is a chronic inflammatory disease. The precise pathophysiology of this disease remains uncertain. Insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1) and polypyrimidine tract-binding protein 1 (PTBP1) have both been found to regulate proliferation, apoptosis, and invasion. This study aimed to investigate the effects of IGF2BP1/PTBP1 in treating EMs.