I am a
Home I AM A Search Login

Papers of the Week

Papers: 16 Mar 2024 - 22 Mar 2024

2024 Feb 29

J Gastrointest Oncol




Inhibition of GABAergic neurons in the paraventricular nucleus of the hypothalamus precipitates visceral pain induced by pancreatic cancer in mice.


Ji NN, Li ZY, Cao S, Pei B, Jin CY, Li YF, Mao P, Jiang H, Fan BF, Xia M


For patients with pancreatic cancer, visceral pain is a debilitating symptom that significantly compromises their quality of life. Unfortunately, the lack of effective treatment options can be attributed to our limited understanding of the neural circuitry underlying this phenomenon. The primary objective of this study is to elucidate the fundamental mechanisms governing visceral pain induced by pancreatic cancer in murine models.