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Papers of the Week
Individualized Pain Treatment in Chronic Pancreatitis (INPAIN): An International, Multicenter, Investigator-initiated, Prospective, Cohort Study.
Authors
Hagn-Meincke R, Dugic A, Agarwal A, Phillips AE, Waage A, Yadav D, Pillai D, Vivian E, de-Madaria E, Niazi IK, Easler J, Frøkjær JB, McNabb-Baltar J, Asferg LK, Faghih M, Montiel MBG, Cook M, Unnisa M, Tarnasky P, Hegyi P, Garg P, Nedergaard RB, Edwards R, Talukdar R, Farheen S, Olesen SS, Jagannath S, Schmidt S, Singh V, Hajnády Z, Drewes AMAbstract
Pain is the foremost complication of chronic pancreatitis (CP), affecting about 70% of patients. However, the pathophysiological understanding and management of CP-related pain is complex, likely as patients have diverse “pain phenotypes” responding differently to treatment. This study aims to develop a bedside test panel to identify distinct pain phenotypes, investigate the temporal evolution, and determine whether they can be used to predict treatment response.