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Papers of the Week

Papers: 30 Sep 2023 - 6 Oct 2023

2023 Oct 06

J Headache Pain




Increased MRI-based Brain Age in chronic migraine patients.


Navarro-González R, García-Azorín D, Guerrero-Peral ÁL, Planchuelo-Gómez Á, Aja-Fernández S, de Luis-García R


Neuroimaging has revealed that migraine is linked to alterations in both the structure and function of the brain. However, the relationship of these changes with aging has not been studied in detail. Here we employ the Brain Age framework to analyze migraine, by building a machine-learning model that predicts age from neuroimaging data. We hypothesize that migraine patients will exhibit an increased Brain Age Gap (the difference between the predicted age and the chronological age) compared to healthy participants.