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Papers of the Week
Increased CX3CL1 in cerebrospinal fluid and ictal serum t-tau elevations in migraine: results from a cross-sectional exploratory case-control study.
Authors
Süße M, Kloetzer C, Strauß S, Ruhnau J, Overeem LH, Bendig M, Schulze J, Reuter U, Vogelgesang A, Fleischmann RAbstract
To date, migraine is diagnosed exclusively based on clinical criteria, but fluid biomarkers are desirable to gain insight into pathophysiological processes and inform clinical management. We investigated the state-dependent profile of fluid biomarkers for neuroaxonal damage and microglial activation as two potentially relevant aspects in human migraine pathophysiology.