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Papers of the Week
Improved polygenic risk prediction in migraine-first patients.
Authors
Torok D, Petschner P, Baksa D, Juhasz GAbstract
Recent meta-analyses estimated 14.6% and 11.2% SNP-based heritability of migraine, compared to twin-heritability estimates of 30-60%. This study aimed to investigate heritability estimates in “migraine-first” individuals, patients for whom G43 (migraine with or without aura) was their first medical diagnosis in their lifetime.