IL18 rs360717 and rs187238 genetic variants are associated with migraine diagnosis.
Authors
Vitali-Silva A, Bello VA, Poli RC, de Oliveira CEC, Lopes MV, Silveira DN, Bossa BB, Espinosa BR, Ahrens TM, Reiche EMV, Simão ANC
Abstract
Migraine is a genetically determined disorder that predisposes to recurrent episodes of headache. Interleukin (IL)-18 is a pro-inflammatory cytokine that seems to play a role in migraine pathophysiology, and its genetic variants could potentially impact susceptibility to migraine.
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