I am a
Home I AM A Search Login

Papers of the Week

Papers: 12 Aug 2023 - 18 Aug 2023

Clinical, Review

Human Studies, Molecular/Cellular, Neurobiology

Cancer Pain

2023 Aug 15

Cochrane Database Syst Rev



Hyperbaric oxygen therapy for late radiation tissue injury.


Lin ZC, Bennett MH, Hawkins GC, Azzopardi CP, Feldmeier J, Smee R, Milross C


This is the third update of the original Cochrane Review published in July 2005 and updated previously in 2012 and 2016. Cancer is a significant global health issue. Radiotherapy is a treatment modality for many malignancies, and about 50% of people having radiotherapy will be long-term survivors. Some will experience late radiation tissue injury (LRTI), developing months or years following radiotherapy. Hyperbaric oxygen therapy (HBOT) has been suggested as a treatment for LRTI based on the ability to improve the blood supply to these tissues. It is postulated that HBOT may result in both healing of tissues and the prevention of complications following surgery and radiotherapy.