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Papers of the Week


Papers: 25 May 2024 - 31 May 2024


2024 May


Discov Med


38798258


36


184

Hyperbaric Lidocaine Aggravates Diabetic Neuropathic Pain by Targeting p38 MAPK/ERK and PINK1/Parkin-Mediated Mitophagy Signaling Pathway.

Authors

Zheng XL, Chen L, Fan CL, Xiao SJ, Chen SB, Yang FM

Abstract

Diabetic neuropathic pain (DNP) is a complication of diabetes mellitus (DM). Hyperbaric lidocaine (HL), a local anesthetics drug, has neurotoxicity. The present study aims to study the effect and molecular mechanisms of HL on spinal nerve injury in DNP.