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Papers of the Week


Papers: 17 Jun 2023 - 23 Jun 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Inflammation/Inflammatory, Itch


2023 Jun 21


JAMA Dermatol


37342057

Hyperactivation of the JAK2/STAT5 Signaling Pathway and Evaluation of Baricitinib Treatment Among Patients With Eosinophilic Cellulitis.

Authors

Morot J, Del Duca E, Chastagner M, Fernandes M, Estrada Y, Lefevre MA, Kanitakis J, Harou O, Jullien D, Nicolas JF, Krueger JG, Vocanson M, Guttman-Yassky E, Villani AP

Abstract

The pathogenesis of eosinophilic cellulitis (EC) is poorly understood, limiting available treatment options. The current treatment paradigm focuses on delayed type 2 hypersensitivity reaction to various triggers.