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Papers of the Week

Papers: 11 Nov 2023 - 17 Nov 2023

2023 Oct 28



Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity: a mouse model of vestibular migraine.


Rahman SM, Guo L, Minarovich C, Moon L, Guo A, Luebke AE


Both enhanced motion-induced nausea and increased static imbalance are observed symptoms in migraine and especially vestibular migraine (VM). Motion-induced nausea and static imbalance were investigated in a mouse model, nestin/hRAMP1, expressing elevated levels of human RAMP1 in the CNS, which enhances CGRP signaling in the nervous system.