Human dorsal root ganglia are either preserved or completely lost after deafferentation by brachial plexus injury.
Authors
Sodmann A, Degenbeck J, Aue A, Schindehütte M, Schlott F, Arampatzi P, Bischler T, Schneider M, Brack A, Monoranu CM, Gräfenhan T, Bohnert M, Pham M, Antoniadis G, Blum R, Rittner HL
Abstract
Plexus injury results in lifelong suffering from flaccid paralysis, sensory loss, and intractable pain. For this clinical problem, regenerative medicine concepts set high expectations. However, it is largely unknown how dorsal root ganglia (DRG) are affected by accidental deafferentation.
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