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Papers of the Week


Papers: 8 Jul 2023 - 14 Jul 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Medical Devices, Neurobiology, Neuromodulation

PAIN TYPE:
Neuropathic Pain


2023 Jul 12


Bioelectron Med


37434246


9


1

High frequency alternating current neurostimulation decreases nocifensive behavior in a disc herniation model of lumbar radiculopathy.

Authors

Dewberry LS, Porche K, Koenig T, Allen KD, Otto KJ

Abstract

The purpose of this study was to evaluate if kilohertz frequency alternating current (KHFAC) stimulation of peripheral nerve could serve as a treatment for lumbar radiculopathy. Prior work shows that KHFAC stimulation can treat sciatica resulting from chronic sciatic nerve constriction. Here, we evaluate if KHFAC stimulation is also beneficial in a more physiologic model of low back pain which mimics nucleus pulposus (NP) impingement of a lumbar dorsal root ganglion (DRG).