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Papers of the Week
Glucocorticoids modify intracranial pressure in freely moving rats.
Authors
Westgate CSJ, Israelsen IME, Kamp-Jensen C, Jensen RH, Eftekhari SAbstract
Glucocorticoids (GCs) are widely prescribed for a variety of inflammatory diseases, but they are also used to treat raised intracranial pressure (ICP) caused by trauma or oedema. However, it is unclear if GCs independently modulate ICP and if GCs are involved in normal ICP regulation. In this study, we aimed to assess the ICP modulatory effects of GCs and their molecular consequences on choroid plexus (CP).