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Papers of the Week
Glucocorticoid signaling mediates stress-induced migraine-like behaviors in a preclinical mouse model.
Authors
Hu YY, Souza R, Muthuraman A, Knapp L, McIntyre C, Dussor GAbstract
Stress is one of the most common precipitating factors in migraine and is identified as a trigger in nearly 70% of patients. Responses to stress include release of glucocorticoids as an adaptive mechanism, but this may also contribute to migraine attacks. Here, we investigated the role of glucocorticoids on stress-induced migraine-like behaviors.