Browse by Audience
Skip to content
Papers of the Week
Genetically-regulated gene expression in the brain associated with chronic pain: relationships with clinical traits and potential for drug repurposing.
Authors
Johnston KJ, Cote AC, Hicks E, Johnson J, Huckins LMAbstract
Chronic pain is a common, poorly-understood condition. Genetic studies including genome wide association studies (GWAS) identify many relevant variants, which have yet to be translated into full understanding of chronic pain. Transcriptome wide association study using transcriptomic imputation (TI) methods such as S-PrediXcan can help bridge this genotype-phenotype gap.