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Papers of the Week


Papers: 18 Mar 2023 - 24 Mar 2023

RESEARCH TYPE:
Clinical


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2023 Mar 16


J Headache Pain


36927366


24


1

Galcanezumab effects on incidence of headache after occurrence of triggers, premonitory symptoms, and aura in responders, non-responders, super-responders, and super non-responders.

Authors

Ashina S, Melo-Carrillo A, Toluwanimi A, Bolo N, Szabo E, Borsook D, Burstein R

Abstract

The goal of this observational, open-label, cohort study was to determine whether prophylactic migraine treatment with galcanezumab, a peripherally acting drug, alters the incidence of premonitory symptoms, and/or occurrence of headache after exposure to triggers or aura episodes in treatment-responders (≥ 50% reduction in monthly migraine days [MMD]), super-responders (≥ 70%), non-responders (< 50%) and super non-responders (< 30%).