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Papers of the Week


Papers: 18 Feb 2023 - 24 Feb 2023

RESEARCH TYPE:
Commentary/Perspective

PAIN TYPE:
Arthritis, Musculoskeletal Pain


2023 Feb 13


Curr Opin Rheumatol


36795021

Fibromyalgia and centralized pain in the rheumatoid arthritis patient.

Authors

Minhas D, Murphy A, Clauw DJ

Abstract

Individuals with rheumatoid arthritis (RA) have traditionally been characterized as having nociceptive pain, leading to the assumption that effective immunosuppression should be enough to provide effective pain management. However, despite therapeutic advancements providing excellent control of inflammation, patients continue to have significant pain and fatigue. The presence of concurrent fibromyalgia, driven by augmented central nervous system processing and largely unresponsive to peripheral therapies, may contribute to this pain persistence. This review provides updates on fibromyalgia and RA as relevant for the clinician.