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Papers of the Week


Papers: 22 Mar 2025 - 28 Mar 2025


2025


Front Pain Res (Lausanne)


40144516


6

Exploring the value of a well-established conditioned pain modulation paradigm in women: a Translational Research in Pelvic Pain (TRiPP) study.

Authors

Demetriou L, Perro D, Coxon L, Krassowski M, Lunde CE, Ferreira-Gomes J, Charrua A, Abreu-Mendes P, Arendt-Nielsen L, Aziz Q, Birch J, Garbutt K, Horne A, Hoffman A, Hummelshoj L, Meijlink J, Obendorf M, Pogatzki-Zahn E, Sasamoto N, Terry K, Treede RD, Vitonis A, Vollert J, Rahmioglu N, Becker CM, Cruz F, Missmer SA, Zondervan K, Sieberg CB, Nagel J, Vincent K

Abstract

Conditioned pain modulation (CPM) is considered a human proxy for descending inhibitory pain pathways. However, there is wide variation in the CPM response described in the literature and ongoing debate about its utility.