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Evidence-Based Umbrella Review of Non-Invasive Neuromodulation in Chronic Neuropathic Pain.
Authors
Duarte-Moreira RJ, Shirahige L, Rodriguez-Prieto IE, Alves MM, Lopes TDS, Baptista RF, Hazime FA, Zana Y, Kubota GT, de Andrade DC, Yeng LT, Teixeira MJ, Dáquer ECMA, Sá KN, Monte-Silva K, Baptista AFAbstract
Non-invasive neuromodulation techniques (NIN), such as transcranial Direct Current Stimulation (tDCS) and repetitive Transcranial Magnetic Stimulation (rTMS), have been extensively researched for their potential to alleviate pain by reversing neuroplastic changes associated with neuropathic pain (NP), a prevalent and complex condition. However, treating NP remains challenging due to the numerous variables involved, such as different techniques, dosages and aetiologies. It is necessary to provide insights for clinicians and public healthcare managers to support clinical decision-making. This umbrella review aims to consolidate existing evidence on the effectiveness of various NIN in managing chronic NP.