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Papers of the Week
Evaluation of F-FAPI-04 Imaging in Assessing the Therapeutic Response of Rheumatoid Arthritis.
Authors
Zhang Q, Lin X, Wang W, Zhang X, Lü M, Shao Z, Shi D, Zhang R, Shi H, Zhang Y, Pan J, Song G, Cheng K, Ge L, Wang L, Han JAbstract
Fibroblast activating protein (FAP) is highly expressed in the synovial tissues of rheumatoid arthritis (RA) patients. The aim of this study was to determine the feasibility of PET imaging with an Al[F] F-NOTA-labeled FAP inhibitor 04(F-FAPI-04) for the evaluation of arthritic progression and therapeutic response in experimental arthritis.