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Papers of the Week


Papers: 7 Dec 24 - 13 Dec 24


2024 Dec 09


Life Sci


39662776

Evaluating the efficacy of intra-articular polydioxanone (PDO) injections as a novel viscosupplement in osteoarthritis treatment.

Authors

Le LTT, Chien PN, Trinh TT, Seo JW, Giang NN, Nga PT, Zhang XR, Jin YX, Nam SY, Heo CY

Abstract

Osteoarthritis (OA) is a chronic joint disorder marked by cartilage breakdown, bone alterations, and inflammation, leading to significant pain and disability. Current therapeutic strategies, ranging from lifestyle interventions to pharmacological and surgical treatments, offer limited efficacy and are often accompanied by side effects. This study investigates the potential of Polydioxanone (PDO), a biocompatible synthetic polymer, as a novel intra-articular (IA) viscosupplement in OA.