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Papers of the Week
Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.
Authors
Wang F, Ye Z, Yin X, Zhou C, Zhong M, Zhao GAbstract
Typically, neuropathic pain (NP) is difficult to manage as it is refractory to conventional medications. Electroacupuncture (EA) at 5/100 Hz has emerged as an effective and promising treatment for NP; however, its mechanism of action is still uncertain. Accordingly, this study investigated the alleviatory mechanism of EA in chronic compression injury (CCI)-induced chronic pain via the C-C chemokine ligand 3 / C-C chemokine receptor type 5 (CCL3/CCR5) axis.