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Papers of the Week


Papers: 9 Nov 2024 - 15 Nov 2024


2024 Nov 11


Chin Med


39529111


19


1

Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia.

Authors

Zheng Y, Jiang M, Wei Z, Chi H, Kang Y, Li S, Zheng Y, He X, Shao X, Fang J, Jiang Y

Abstract

Sciatica and low back pain are prevalent clinical types of neuropathic pain that significantly impair patients’ quality of life. Conventional therapies often lack effectiveness, making these conditions challenging to treat. Electroacupuncture (EA) is an effective physiotherapy for pain relief. Prior research has demonstrated a relationship between the frequency of neuropathic pain and the analgesic impact of EA stimulation. This work aimed to assess the analgesic effects of EA in a rat model of chronic compression of the dorsal root ganglion (CCD) and to understand the underlying processes.