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Papers of the Week
Electroacupuncture alleviates mechanical allodynia and anxiety-like behaviors induced by chronic neuropathic pain via regulating rostral anterior cingulate cortex-dorsal raphe nucleus neural circuit.
Authors
Xu Y, Zhu X, Chen Y, Chen Y, Zhu Y, Xiao S, Wu M, Wang Y, Zhang C, Wu Z, He X, Liu B, Shen Z, Shao X, Fang JAbstract
Epidemiological studies in patients with neuropathic pain have demonstrated a strong association between neuropathic pain and psychiatric conditions such as anxiety. Preclinical and clinical work has demonstrated that electroacupuncture (EA) effectively alleviates anxiety-like behaviors induced by chronic neuropathic pain. In this study, a potential neural circuitry underlying the therapeutic action of EA was investigated.