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Papers of the Week

Papers: 1 Jul 2023 - 7 Jul 2023

Clinical, Psychology

Human Studies, Molecular/Cellular, Neurobiology, Neuromodulation

Neuropathic Pain, Psychological/Comorbidities

2023 Jul 03

CNS Neurosci Ther


Electroacupuncture alleviates mechanical allodynia and anxiety-like behaviors induced by chronic neuropathic pain via regulating rostral anterior cingulate cortex-dorsal raphe nucleus neural circuit.


Xu Y, Zhu X, Chen Y, Chen Y, Zhu Y, Xiao S, Wu M, Wang Y, Zhang C, Wu Z, He X, Liu B, Shen Z, Shao X, Fang J


Epidemiological studies in patients with neuropathic pain have demonstrated a strong association between neuropathic pain and psychiatric conditions such as anxiety. Preclinical and clinical work has demonstrated that electroacupuncture (EA) effectively alleviates anxiety-like behaviors induced by chronic neuropathic pain. In this study, a potential neural circuitry underlying the therapeutic action of EA was investigated.