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Papers of the Week


Papers: 15 Apr 2023 - 21 Apr 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology

PAIN TYPE:
Inflammation/Inflammatory, Musculoskeletal Pain


2023 Apr


Br J Pain


37057258


17


2

Efficiency of pain inhibition and facilitation of fibromyalgia patients is not different from healthy controls: Relevance of sensitivity-adjusted test stimuli.

Authors

Staud R, Godfrey MM, Riley JL, Fillingim RB

Abstract

Pain is a dynamic phenomenon dependent on the balance of endogenous excitatory and inhibitory systems, which can be characterized by quantitative sensory testing. Many previous studies of pain modulatory capacity of patients with fibromyalgia syndrome (FM) have reported decreased pain inhibition or increased pain facilitation. This is the first study to assess pain modulation, including conditioned pain modulation (CPM) and temporal pain summation, in the same healthy control (HC) and FM participants.