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Papers of the Week
Efficacy of Tirzepatide Dual GIP/GLP-1 Receptor Agonist in Patients With Idiopathic Intracranial Hypertension. A Real-World Propensity Score-Matched Study.
Authors
Azzam AY, Essibayi MA, Farkas N, Azab MA, Morsy MM, Elamin O, Elswedy A, Al Zomia AS, Alotaibi HA, Alamoud A, Atallah O, Abukhadijah HJ, Dmytriw AA, Baker A, Khatri D, Haranhalli N, Altschul DJAbstract
Idiopathic intracranial hypertension (IIH) is a neurological disorder characterised by elevated intracranial pressure (ICP), predominantly affecting obese women of reproductive age. While GLP-1 receptor agonists have shown promise in IIH management, the potential of dual GIP/GLP-1 receptor activation through tirzepatide remains unexplored. This study aimed to evaluate tirzepatide’s efficacy as an adjunctive therapy in IIH management.