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Papers of the Week


Papers: 18 Mar 2023 - 24 Mar 2023

RESEARCH TYPE:
Psychology, Translational


Human Studies

PAIN TYPE:
Psychological/Comorbidities


2023 Mar 18


Eur J Pain


36932915

Efficacy of open-label counterconditioning for reducing nocebo effects on pressure pain.

Authors

Meijer S, Karacaoglu M, van Middendorp H, Veldhuijzen DS, Jensen KB, Peerdeman KJ, Evers AWM

Abstract

Nocebo effects can adversely affect the experience of physical symptoms, such as pain and itch. Nocebo effects on itch and pain have shown to be induced by conditioning with thermal heat stimuli and reduced by counterconditioning. However, open-label counterconditioning, in which participants are informed about the placebo content of the treatment, has not been investigated, while this can be highly relevant for clinical practice. Furthermore, (open-label) conditioning and counterconditioning has not been investigated for pain modalities relevant to musculoskeletal disorders, such as pressure pain.