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Papers of the Week
Efficacy of Immunotherapy for Complex Regional Pain Syndrome: A Narrative Review.
Authors
Kaye AD, Nguyen A, Boullion J, Blue MF, Allen DWH, Kelkar RA, Mouhaffel A, Ro AT, Ahmadzadeh S, Shekoohi S, Robinson CLAbstract
Complex regional pain syndrome (CRPS) is a chronic condition characterized by disproportional pain typically affecting an extremity. Management of CRPS is centered around specific symptomatology, which tends to be a combination of autonomic dysfunction, nociceptive sensitization, chronic inflammation, and/or motor dysfunction. Targeting the autoimmune component of CRPS provides a way to both symptomatically treat as well as minimize progression of CRPS.