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Papers of the Week


Papers: 11 Mar 2023 - 17 Mar 2023

RESEARCH TYPE:
Clinical


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Inflammation/Inflammatory, Itch


2023 Mar 09


Dermatol Ther (Heidelb)


36892753

Efficacy and Safety of Risankizumab for the Treatment of Hidradenitis Suppurativa: A Phase 2, Randomized, Placebo-Controlled Trial.

Authors

Kimball AB, Prens EP, Passeron T, Maverakis E, Turchin I, Beeck S, Drogaris L, Geng Z, Zhan T, Messina I, Bechara FG

Abstract

Hidradenitis suppurativa (HS) is a chronic, immune-mediated skin condition characterized by inflammatory lesions that can cause pain, impaired physical activity, and reduced quality of life. This study evaluated the efficacy and safety of risankizumab, a humanized immunoglobulin G1 monoclonal antibody that specifically inhibits interleukin 23 by binding to its p19 subunit, for the treatment of HS.