Efficacy and safety of antidepressants for pain in older adults: A systematic review and meta-analysis.
Authors
Narayan SW, Naganathan V, Vizza L, Underwood M, Ivers R, McLachlan AJ, Zhou L, Singh R, Tao S, Xi X, Abdel Shaheed C
Abstract
In many countries, pain is the most common indication for use of antidepressants in older adults. We reviewed the evidence from randomized controlled trials on the efficacy and safety of antidepressants, compared to all alternatives for pain in older adults (aged ≥65 years).
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