Effects of pharmacogenetic profiles on pediatric pain relief and adverse events with ibuprofen and oxycodone.
Authors
Ali S, Yukseloglu A, Ross CJ, Rosychuk RJ, Drendel AL, Manaloor R, Johnson DW, Le May S, Carleton B
Abstract
Individual genetic variation may influence clinical effects for pain medications. Effects of CYP2C9, CYP3A4, and CYP2D6 polymorphisms on clinical effectiveness and safety for ibuprofen and oxycodone were studied.
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