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Papers of the Week
Effects of conditioned pain modulation on Capsaicin-induced spreading muscle hyperalgesia in humans.
Authors
Schliessbach J, Siegenthaler A, Graven-Nielsen T, Arendt-Nielsen L, Curatolo MAbstract
Muscle pain can be associated with hyperalgesia that may spread outside the area of primary injury due to both peripheral and central sensitization. However, the influence of endogenous pain inhibition is yet unknown. This study investigated how endogenous pain inhibition might influence spreading hyperalgesia in experimental muscle pain.