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Papers of the Week


Papers: 19 Oct 2024 - 25 Oct 2024


2024 Oct 16


J Headache Pain


39415097


25


1

Effect of fasting-induced headache on calcitonin gene related peptide (CGRP) and other clinical biomarkers on the first day of Ramadan: Sub-analysis from a randomized open label clinical trial.

Authors

Alwhaibi A, Alasmari F, Almutairi F, Assiri MA, Aldawsari FS, Aloyayd ST, Alhejji AA, Alotaibi JA, Albilali A, Almohammed OA, Alsanea S

Abstract

Fasting-induced headaches (FIHs) have been shown to occur on the first day of Ramadan and clearly decline thereafter. Despite the wealth of knowledge about different types of headaches (e.g., migraine-, cluster-, and tension-type headaches), research on the mechanism underlying FIHs, as well as their treatment, remains scarce. Our study aimed to investigate any association between FIHs during the first day of Ramadan and potential headache-related biomarkers, including fasting blood glucose (FBG), C-reactive protein (CRP), magnesium, vitamin B9, vitamin B12, homocysteine, and calcitonin gene related peptide (CGRP), and to assess whether a prophylactic use of paracetamol may influence these biomarkers.