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Papers of the Week


Papers: 30 Nov 2024 - 6 Dec 2024


2025 Jan


Eur J Pain


39629978


29


1

E-52862-A selective sigma-1 receptor antagonist, in peripheral neuropathic pain: Two randomized, double-blind, phase 2 studies in patients with chronic postsurgical pain and painful diabetic neuropathy.

Authors

Gálvez R, Mayoral V, Cebrecos J, Medel FJ, Morte A, Sust M, Vaqué A, Montes-Pérez A, Neira-Reina F, Cánovas L, Margarit C, Bouhassira D

Abstract

We report the efficacy and safety of E-52862-a selective, sigma-1 receptor antagonist-from phase 2, randomized, proof-of-concept studies in patients with moderate-to-severe, neuropathic, chronic postsurgical pain (CPSP) and painful diabetic neuropathy (PDN).