I am a
Home I AM A Search Login

Papers of the Week


Papers: 25 Jan 2025 - 31 Jan 2025


2025 Jan 14


Biomedicines


39857775


13


1

Differential Gene Expression Analysis in a Lumbar Spinal Stenosis Rat Model via RNA Sequencing: Identification of Key Molecular Pathways and Therapeutic Insights.

Authors

Hong JY, Jeon WJ, Kim H, Yeo C, Kim H, Lee YJ, Ha IH

Abstract

Lumbar spinal stenosis (LSS) is a degenerative condition characterized by the narrowing of the spinal canal, resulting in chronic pain and impaired mobility. However, the molecular mechanisms underlying LSS remain unclear. In this study, we performed RNA sequencing (RNA-seq) to investigate differential gene expression in a rat LSS model and identify the key genes and pathways involved in its pathogenesis.