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Papers of the Week
Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study.
Authors
Pijpers JA, Kies DA, van Zwet EW, de Boer I, Terwindt GMAbstract
Central sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third order neurons sequentially, resulting in an analogous spatial distribution of cutaneous allodynia with cephalic and extracephalic symptoms. We investigated whether allodynia, and its subtypes based on spatial distribution and type of stimulus, predict response to treatment in chronic migraine patients.