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Papers of the Week

Papers: 27 Jan 2024 - 2 Feb 2024

2024 Jan 27

Neurosci Lett


COX2 expression plays a role in spinal cord injury-induced neuropathic pain.


Toi M, Toshiya T, Noguchi K, Yamanaka H, Kobayashi K, Okubo M, Kishima K, Dai Y


Elucidating the mechanism of neuropathic pain (NeP) is crucial as it can result in motor dysfunction and negatively impact quality of life in patients with spinal cord injury (SCI). Although it has been reported that cyclooxygenase 2 (COX2) is involved in NeP in rat models of peripheral nerve injury and that COX2 inhibitors can alleviate NeP, these mechanisms after SCI have not been fully investigated.