I am a
Home I AM A Search Login

Papers of the Week


Papers: 4 Feb 2023 - 10 Feb 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Pharmacology/Drug Development


2023 Feb 01


Br J Anaesth


36737387

Corticotropin-releasing factor neurones in the paraventricular nucleus of the hypothalamus modulate isoflurane anaesthesia and its responses to acute stress in mice.

Authors

Xu Z, Hu SW, Zhou Y, Guo Q, Wang D, Gao YH, Zhao WN, Tang HM, Yang JX, Yu X, Ding HL, Cao JL

Abstract

Corticotropin-releasing factor (CRF) neurones in the paraventricular nucleus (PVN) of the hypothalamus (PVN neurones) can promote wakefulness and are activated under anaesthesia. However, whether these neurones contribute to anaesthetic effects is unknown.