I am a
Home I AM A Search Login

Papers of the Week


Papers: 16 Sep 2023 - 22 Sep 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Genetics, Molecular/Cellular, Neurobiology, Sex Differences

PAIN TYPE:
Neuropathic Pain


2023 Sep 18


Life Sci


37730112

CoREST1 in primary sensory neurons regulates neuropathic pain in male mice.

Authors

Zhou X, Wei J, Cheng H, Tian L, Zhu X, Zhang Y, Xu L, Wei G, Huo FQ, Liang L

Abstract

Epigenetic regulation is implicated in the neurogenesis of neuropathic pain. The repressor element 1 (RE1) silencing transcription factor (REST) corepressor (CoREST) proteins function as corepressors in the REST complex and/or LSD1 epigenetic complex. In the current study, we aimed to find the expression profile of CoREST1 in the dorsal root ganglion (DRG) and investigate whether it plays a role in neuropathic pain.